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fadH [2017-8-11 16:0:3]
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fadH [2017-8-11 16:0:3]

2,4-dienoyl-CoA reductase
Locus
BSU14060
Isoelectric point
6.49
Molecular weight
26.98 kDa
Protein length
254 aa Sequence Blast
Gene length
762 bp Sequence Blast
Function
fatty acid degradation
Product
2,4-dienoyl-CoA reductase
Essential
no
E.C.
1.3.1.34
Synonyms
ykuF

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,478,072 → 1,478,836

The protein

Catalyzed reaction/ biological activity

  • Trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH (according to Swiss-Prot)
  • Protein family

  • 2,4-dienoyl-CoA reductase subfamily (according to Swiss-Prot)
  • Paralogous protein(s)

    Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • FadR: repression, PubMed, in FadR regulon
  • Regulation

  • induced in the presence of long-chain fatty acids (FadR) PubMed
  • expression of the operon is strongly induced during biofilm formation PubMed
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    Biological materials

    Mutant

  • MGNA-B336 (ykuF::erm), available at the NBRP B. subtilis, Japan
  • References

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